Recombinant Proteins
Recombinant Human Low Density Lipoprotein Receptor Related Protein 5 (LRP5)
Product Description
Recombinant Human Low Density Lipoprotein Receptor Related Protein 5 (LRP5), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques.
Scientific Background
Low-density lipoprotein receptor-related protein 5(LRP5) is a protein that in humans is encoded by the LRP5 gene. LRP5 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. Mutations in LRP5 can lead to considerable changes in bone mass. LRP5 acts as a co-receptor with LRP6 and the Frizzled protein family members for transducing signals by Wnt proteins through the Canonical Wnt Pathway. This protein plays a key role in skeletal homeostasis.
| Catalouge No. | RP2041 |
|---|---|
| Pack Size | 100 µg |
| Formulation Buffer | 20mM Tris,150mM NaCl,pH8.0,containing 1mM EDTA,1mM DTT,0.01% SKL, 5% Trehalose and Proclin300. |
| Purity | > 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~33KDa |
| Storage | Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
| Regulatory | For research use only (RUO) |