Recombinant Proteins
Recombinant Human Transmembrane Protein 173 (TMEM173)
Product Description
Recombinant Human Transmembrane Protein 173 (TMEM173), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques.
Scientific Background
Transmembrane Protein 173 (TMEM173) gene encodes the protein STING (stimulator of interferon genes), a key player in host defense against pathogens. Mutations in the human TMEM173 gene cause a life-threatening auto-inflammatory disease called SAVI (STING-associated vasculopathy with onset in infancy). Human STING is also a promising therapeutic target for cancers and infectious diseases.
| Catalouge No. | RP2017 |
|---|---|
| Pack Size | 100µg |
| Formulation Buffer | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300 |
| Purity | > 97% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~30 KDa |
| Storage | Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
| Regulatory | For research use only (RUO) |