In diagnostics, trust is everything. A single unreliable reagent, inconsistent antibody pair, or delayed shipment can derail entire validation pipelines. For diagnostic manufacturers competing in a fast-moving global market, consistency…
In diagnostics, choosing the right antigen determines the difference between ambiguous results and clear, actionable insights. This is especially true for two critical markers: Native CRP (C-Reactive Protein) HBsAg Ad/Ay…
Detecting neutralizing anti-etanercept antibodies is essential for accurate anti-drug antibody (ADA) and cell-based assays. These antibodies can directly negate the biologic activity of etanercept, affecting efficacy, pharmacokinetics, safety, and clinical outcomes. In this article, we…
In the competitive world of diagnostics, every decision - from assay design to reagent selection, impacts product success. For diagnostic manufacturers, accuracy is non-negotiable. And at the heart of accuracy lies…
In diagnostic manufacturing, speed and cost pressures often tempt manufacturers to cut corners on antibody selection. However, using unvalidated antibody pairs, especially in Lateral Flow Assays (LFAs) for targets like Dengue NS1…
Importance of antibody pair validation in LFA development Rapid diagnostic tests, especially lateral flow immunoassays (LFIAs) are critical for early detection of viruses like Dengue NS1 and HBsAg, particularly in resource-limited settings. But…
Envelope proteins are viral glycoproteins embedded in the outer membrane of enveloped viruses like coronavirus, influenza, HIV, and HCV. Such proteins like spike (S), envelope (E), and membrane (M) mediate…
Understanding TNF-α in Diagnostics Tumor Necrosis Factor-alpha (TNF-α) is a central cytokine in inflammation and immune signaling. Dysregulated TNF-α levels are implicated in autoimmune diseases such as rheumatoid arthritis, psoriasis,…
In diagnostic assay development, sensitivity is everything. Whether you are working on infectious disease screening, biomarker detection, or therapeutic monitoring, the ability to detect analytes at ultra-low concentrations can make…
This is how 'Native CRP Protein' and 'HBsAg Ad/Ay Antigens' are powering diagnostics Introduction In the diagnostic landscape, precision starts with high-quality reagents. Two critical components, C-reactive protein (CRP) for inflammation…
Why ADA Detection? Biologic therapies such as etanercept (a TNF-α inhibitor widely prescribed for autoimmune diseases like rheumatoid arthritis, ankylosing spondylitis, and psoriasis) have transformed patient outcomes. However, one major challenge limits…
Scaling from the lab bench to full-scale manufacturing is one of the most exciting and most challenging stages for diagnostic developers. You have validated your assay in R&D, the results…
