Recombinant Proteins
Recombinant Human Cholinergic Receptor, Nicotinic, Alpha 7 (CHRNa7)
Product Description
Recombinant Human Cholinergic Receptor, Nicotinic, Alpha 7 (CHRNa7), expressed in Escherichia coli (E. coli) and purified by standard chromatographic techniques.
Scientific Background
Cholinergic Receptor, Nicotinic, Alpha 7 (CHRNa7) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
| Catalouge No. | RP2040 |
|---|---|
| Pack Size | 100 µg |
| Formulation Buffer | 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% skl, 5%Trehalose. |
| Purity | > 90% pure as determined by Silver stained SDS-PAGE analysis. Molecular Weight: ~54KDa |
| Storage | Shipped at 2-8°C. Aliqote and Storet at-80C; Avoid repeated freeze/thaw cycles. |
| Regulatory | For research use only (RUO) |